The researchers suggest certain refinements to the 2022 European LeukemiaNet classification model ... a more targeted approach to treating acute myeloid leukemia (AML) based on accumulating ...

Secondary acute myeloid leukemia (AML) is a blood cancer that arises from other blood disorders or previous cancer treatment. Those with secondary AML tend to have a less favorable outlook than ...

Researchers sought to determine whether DNA methylation markers could be helpful in risk stratification for patients with AML and normal cytogenetics.

Molecular approaches applicable at presentation with leukemia support diagnosis, classification, prognostication, stratification and identification of therapeutic targets. Genetic analysis in ...

THRAP3, STMN1, and GNA13—are overrepresented in blood cancers like acute myeloid leukemia (AML) and could prove to be novel ...

The FDA has granted fast track designation to HC-7366 for the treatment of adult patients with relapsed/refractory acute ...

Oct. 9, 2024 — Researchers have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions. The technology accurately ...

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment. A new editorial paper was published in Oncotarget's ...

1 A paper by Cronkite 2 (1961) summarizes the natural history of "benzene leukemia ... chromosomes of the first two groups of the Denver classification gave evidence of deletions; polyploidism ...

In the field of myelodysplastic syndromes (MDS), there are a number of investigational studies designed with the hope of ...

A new study reveals a modular CAR-T approach that effectively targets heterogeneous antigens in paediatric acute myeloid leukaemia, enhancing treatment success through combinatorial targeting.