The properties of the different IgG isotypes should be considered in developing therapeutic antibodies. To address this problem, antibody engineers introduced a serine-to-proline substitution that ...

For example, secondary antibodies that react with IgG (H+L) will react with epitopes on both heavy and light chains, so they will react with other isotypes of primary antibody or different subtypes of ...

How different antibody isotypes, such as immunoglobulin G, A and M, arise and persist after exposure to antigens is a subject of intense investigation. Luminex, a DiaSorin company focused on ...

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, today announced the launch of its isotype-specific secondary antibodies.

It also supports simultaneous analysis of up to two antibody isotypes, delivering greater depth and breadth of understanding into disease pathways and mechanisms. You can access i-Ome Discovery ...

Objectives: To determine exercise induced changes in the adaptive immune system by measuring the immunoglobulin isotype and subclass response to an ultra-marathon. Methods: Venepuncture was performed ...