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A 'chemical metronome': Researchers uncover how astrocytes help the brain's master clock keep timeThey found that astrocytes regularly release a neurotransmitter called GABA, which peaked every 24-hours. This regular pulse was found to act as a kind of chemical metronome, helping to ...
This image is a microscopic view showing high concentrations of the GABA neurotransmitter (red) in the reactive astrocytes (green) in a human brain with Alzheimer's disease. The image credit must ...
At the centre of this research are astrocytes - star-shaped brain cells that act as the brain's supervisors. These cells manage a crucial molecule called GABA through a specialised transporter (GAT-3) ...
In a recent study published in PNAS, Zhang showed that the transcription factor DLX2 can convert astrocytes into progenitors that produce various cell types, including neurons. 3 These findings ...
Traumatic brain injury, stroke, and degenerative diseases elicit complex pathogenic cascades involving glial cells such as astrocytes, microglia, and ...
Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...
2019b). Also, affected twins showed altered NMDA and GABA calcium responses which were normalized with antipsychotic drug clozapine. Later we showed similar results with astrocyte cultures (Koskuvi, ...
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