Inside the nucleus of a cell, the chromatin fiber interacts with itself to condense into a chromosome. The chromatin fiber also supports gene expression and replication of chromosomal DNA.

Inside the nucleus of a cell, the chromatin fiber interacts with itself to condense into a chromosome. The chromatin fiber also supports gene expression and replication of chromosomal DNA.

The INO80 complex normally functions in the nucleus to rearrange chromatin ¬- the intertwined proteins and DNA that are packaged into chromosomes -- regulating the expression of many different genes.

To fit the two meters of DNA that comprises the genome within just one hundredth of a millimeter of space inside a cell’s nucleus ... which dictates how the cell functions. Throughout one’s life, ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Imaging Chromatin to Deduce Function from Form. Researchers describe their tools for probing how the physical shape of the genome affects genes’ function. ... 1860, provide one of the first ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Using computer simulations, MIT chemists have now discovered how these bodies interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets within ...

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a single speck of dust. Despite its density, DNA is not a tangled ball of yarn.

Inside a nucleus, chromosomes jumble together like a game of Twister. This can bring regulatory elements, such as enhancers, from one chromosome into contact with genes from another chromosome, ...