Han-Seok Seo et al. Effects of Coffee Bean Aroma on the Rat Brain Stressed by Sleep Deprivation: A Selected Transcript- and 2D Gel-Based Proteome Analysis. Journal of Agricultural and Food ...

The coffee-sniffing sleep-deprived rats showed different levels of activity in 17 genes in the brain. Levels of some brain proteins also changed in ways that could have a calming effect on stress ...

The Best Way to Use Coffee Grounds Before You Toss Them As much as I'd love to chalk it up to coffee just being magical, there's real science behind this odor-fighting trick.