But in the POPE-2 study, in which we had to screen over 8,000 individuals to identify 197 cases, colchicine was no better than placebo at reducing the effusion and the risk of cardiac tamponade." ...

They reported that on multivariable analysis, the predictors of survival were tamponade being the cause of TCA (adjusted OR 21.1, 95% CI 8.1-54.7) and duration of TCA <1 minute (adjusted OR 20.9 ...

In post-hoc analyses, the composite outcome of clinically important perioperative AF or MINS occurred in 360 (22.4%) patients in the colchicine group and in 415 (25.9%) patients in the placebo ...

The study included 99,800 patients with gout (25.6% women; mean age, 62.8 years), 16,028 of whom were prescribed at least 21 days of colchicine on the same date as urate-lowering therapy, while ...

The FDA recently approved the first anti-inflammatory drug for cardiovascular disease called LODOCO (colchicine). The recently approved medication has been shown to reduce cardiac event risk in ...

Although cardiac surgery is safe, cardiac tamponade can come on quickly – usually after the patient has left theatre, and typically late at night when the patient is in intensive care.

As I read the guidelines, I found that I am at a moderate to high risk for a future cardiac event. Adding 0.5 mg of colchicine to my medication regimen could potentially result in a substantial ...