Cytoglobin (Cygb) was first described in 2002 as an intracellular globin of unknown function. We have previously shown the downregulation of cytoglobin as a key event in a familial cancer syndrome ...

Yu XL, Gao DW. Overexpression of the cytoglobin gene inhibits hypoxic injury to SH-SY5Y neuroblastoma cells. Neural Regen Res. 2013;8 (23):2198-2203. Contact: Meng Zhao [email protected] 86-138-049-98773 ...

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice. CYGB, discovered in 2001 by Professor Norifumi Kawada, is ...

Cytoglobin is a recently identified vertebrate globin whose functions include scavenging reactive oxygen and nitrosative species. In tumor cells, CYGB may function as a tumor suppressor gene. Here we ...

Cytoglobin, akin to hemoglobin plays a vital role in shaping the heart's left-right pattern and asymmetric organ development, stated University of Maryland School of Medicine study. Published in ...

Cytoglobin regulates NO-dependent cilia motility and organ laterality during development. Nature Communications, 2023; 14 (1) DOI: 10.1038/s41467-023-43544-0 ...

This is the first time cytoglobin – or any of the globin proteins like hemoglobin – has been found to be involved in fetal development and that a paucity could be linked to birth defects.

Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice. CYGB, discovered in 2001 by Professor Norifumi Kawada, is ...

The study, published in Nature Communications, used CRISPR in zebrafish to remove the gene for cytoglobin. Researchers found it led to defects in the structure and location of organs in developing ...

Then, the recombinant plasmid was transfected into SH-SY5Y cells. Xiuling Yu and colleagues found that overexpression of cytoglobin could protect SH-SY5Y cells against cobalt chloride-induced hypoxia.

Prominent members include Hemoglobin, Myoglobin, Neuroglobin, Cytoglobin. Story Source: Materials provided by Osaka City University. Note: Content may be edited for style and length. Journal ...