DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Human polymerase θ helicase positions DNA microhomologies for double-strand break repair. Nature Structural & Molecular Biology , 2025; DOI: 10.1038/s41594-025-01514-8 Cite This Page : ...

The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. ... Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells. 3d.

Correction 6/18/21: The original version of this article stated that polymerase theta was the first mammalian polymerase with the ability to transcribe RNA into DNA. In fact, other polymerases ...

Researchers show that polymerase theta can efficiently convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells. Editor's Note: Thomas Jefferson University issued ...

Pomerantz’s team started by investigating an unusual polymerase, polymerase theta. Of the 14 DNA polymerases in mammalian cells, only three do the bulk of the work of replicating the genome ...

Not unlike patching a tire, the job of DNA polymerase theta (aka Pol theta) is to fix double-strand breaks in DNA, bridging the hanging single-stranded ends and catalyzing DNA synthesis across the ...

The misunderstood polymerase theta has been shown to be able to read RNA back into DNA in mammalian cells, ... Sign up for our webinar on enhancing protein purification efficiency! 21 days 5 hours 21 ...