Scientists have reached a new milestone in decoding the human genome, unlocking complex regions once believed to be too difficult to study. Researchers used long-read sequencing to analyze the DNA of ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

A new study shows that over 99% of the human genome can be accurately assembled by focusing on 65 diverse humans.

Their findings, published in the Proceedings of the National Academy of Sciences, pave the way for solid-state, label-free DNA sequencing technologies with implications for precision medicine ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars ...

Thus, elevated sequencing errors at non-B DNA motifs should be considered in low-read-depth studies (single-cell, ancient DNA, and pooled-sample population sequencing) and when scoring rare variants.

In the late 2000s, IBM proposed the idea of DNA transistors, conceptualized with a dielectric metal sandwich structure and electrostatic traps to simultaneously allow ratchet-like control and sensing ...