Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of ...

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix.

The mice upregulated extracellular matrix (ECM) proteins and the ECM upstream regulator TGF-β1 (image above). Spinal cord, but not cortical, neurons contained 50 percent more of the type VI collagen ...

Lophius/Getty Different animals have different types of extracellular matrix. But the extracellular matrices of jellyfish resemble those of many other animals, including dinosaurs and humans.

“The extracellular matrix is critical for maintaining the structure and function of the skin and other tissues, acting as a barrier to the entry of microorganisms and toxins,” Hidalgo explained.

Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk. Med, 2023; 4 (8): 554 DOI: 10.1016/j.medj.2023.07.004 ...

More information: Hyeonji Kim et al, Extracellular matrix-based sticky sealants for scar-free corneal tissue reconstruction, Biomaterials (2022). DOI: 10.1016/j.biomaterials.2022.121941 ...

Thin and stretchable extracellular matrix (ECM) membrane reinforced by nanofiber scaffolds for developing in vitro barrier models. Biofabrication, 2022; 14 (2): 025010 DOI: 10.1088/1758-5090/ac4dd7 ...