One of the major constituents of the cell-adhesion complex in epithelial cells is E-cadherin, a transmembrane protein involved in homotypic cell–cell adhesion. E-cadherin exerts a potent ...
Assessment of cadherin-11 as a therapeutic target was also performed in mice with established arthritis, and administration of a monoclonal antibody towards cadherin-11 ameliorated the arthritis.
SOTIO Biotech, a clinical-stage biopharmaceutical company owned by PPF Group, today presented the first preclinical data on SOT109, a novel antibody-drug conjugate (ADC) targeting cadherin-17 (CDH17).
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