How proteins in our cells attain their correct three-dimensional structure is crucial to their function—and to our health.

The endoplasmic reticulum (ER) of columella root cap cells has been postulated to play a role in gravity sensing. We have re-examined the ultrastructure of columella cells in tobacco (Nicotiana ...

We found that endoplasmic reticulum stress markers, activating transcription factor 6, inositol-requiring enzyme 1a, protein kinase RNA-like endoplasmic reticulum kinase, C/EBP homologous protein, and ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Emerging research positions TUDCA, a bile acid compound, as a promising neuroprotective agent against Alzheimer’s, ...

With a new method, researchers have captured a high-resolution metabolic “map” of how cells orchestrate glucose processing, ...

Journal reference: Estébanez, B., et al. (2022) Resistance Training Modulates Reticulum Endoplasmic Stress, Independent of Oxidative and Inflammatory Responses, in Elderly People.

How proteins in our cells attain their correct three-dimensional structure is crucial to their function—and to our health.

Sepsis-induced immune dysfunction is a major contributor to high mortality rates in septic patients. Recent findings shed light on the role of ...