Researchers explored the role of the minor intron-containing gene (MIG)-encoded proteins (MIG-Ps) depending on minor spliceosome-MiG excision to be expressed in infections by pathogenic viruses.

More information: Yi Li et al, Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates, Cell Research (2025). DOI: 10.1038/s41422-025-01084-w ...

This spliceosome is made up of variety of protein and RNA components, and for each splicing process, it is reassembled at the sites where an exon joins an intron and the intron in turn connects to ...

All the latest science news on intron from Phys.org. Find the latest news, ... RNA splicing is a cellular process that is critical for gene expression. ... The minor spliceosome: ...

The research team offers a solution to this enigma by demonstrating that SPF45 is a novel and distinct constitutive splicing factor in the early spliceosome, i.e., a subset of human short introns ...

Besides the Boehringer deal, ExpressionEdits is open to exploring other relationships with others in the gene therapy space, specifically larger, more mature companies. “We don’t have the ...