New method of analysis reveals that transposable elements (TEs), which make up 45% of the human genome, play a crucial role ...

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Medically reviewed by Anju Goel, MD Deoxyribonucleic acid (DNA) is the material in cells that carries all genetic information in humans, animals, plants, and all living cells. It’s passed down from ...

DNA—> RNA—> Protein—> Phenotype The dogma was enshrined in Jim Watson’s 1965 epic textbook The Molecular Biology of the Gene.

The guide RNA-target DNA heteroduplex is bound to the groove between the REC and NUC lobes. Credit: Nature (2023). DOI: 10.1038/s41586-023-05933-9 ...

However, my team and I discovered that RNA, a type of genetic material best known for its role in making proteins, surprisingly plays a key role in facilitating the repair of these harmful breaks.

Children who develop deep wrinkles, stunted growth, and rapidly aging bones and blood vessels as early as 1 to 2 years of age ...

In a recent study by the team, they discovered the 3D structure of a protein called TnpB, a probable precursor to the CRISPR-Cas12 enzyme. Their findings appeared in the journal Nature.