Labroots

Keynote Presentation: Immuno-Oncology Application of Humanized Immune System (HIS) Mice Supporting Human Myeloid and Lymphoid Cells

Since the development of the super immunodeficient CIEA NOG mouse® in the early 2000s enabled improved humanized immune system (HIS) mice, HIS models have been widely adopted in immuno-oncology ...
GEN

Optimizing Humanized Mice for Immuno-Oncology: Advancing CAR T Research

In the rapidly advancing field of immuno-oncology research, there has been increasing focus on the utility and optimization of cell humanized mice for translational research. Conventional murine ...
GEN

Leveraging Flow Cytometry to Accelerate Research Using Humanized Immune System Mice

Flow cytometry enables researchers to label proteins of interest using fluorophore-conjugated antibodies and other fluorochromes. Much like immunohistochemistry, which produces two- or ...
Labroots

Keynote Presentation: Humanized Immune System (HIS) Mice for NK and T Cells: Applications for Cell Therapies and Immune Modulators with Live Q&A

Humanized immune system (HIS) mice are invaluable for advancing preclinical research, with various models available to support lymphoid, myeloid and/or specific cell populations. T and NK cells are ...
ascopubs.org

Engineering PBAE nanoparticles for immunological reprogramming in clinically relevant humanized mouse models.

Desmoplastic nodular medulloblastoma: A National Cancer Database analysis of patient demographics and survival. A phase 1 study to evaluate the safety and tolerability of BXQ-350, a novel sphingolipid ...