Inherited platelet disorders represent a heterogeneous group of genetic conditions that affect the number, size, or function of platelets, with clinical manifestations ranging from mild ...

A low platelet count can be caused by genes inherited from your parents. More than 40 genes have been linked to hereditary thrombocytopenia, and more genes will likely be discovered in the future.

About the Research In this study, the authors assessed platelet and red blood cell (RBC) features using immunofluorescence microscopy in 135 MPN patients and 83 healthy subjects. They used a panel ...

Even as biomedical engineer Anirban Sen Gupta refines artificial platelets to stem traumatic bleeding, he and his colleagues are seeking new uses for their synthetic solution. The latest application ...

The model may help clinicians predict which patients will benefit from a new therapy for blood platelet disorders, such as Inherited Thrombocytopenias -- a group of familial disorders that inhibit ...

The main types of noncancerous blood disorders are blood clotting disorders, bleeding or platelet disorders, anemia, and eosinophilic disorders, which are problems with a type of white blood cell. [1] ...

Inherited platelet disorders are recognized as an important cause of mild to severe bleeding in both children and adults. Treatment of platelet disorders is mainly supportive.

Thrombocytopenic disorders are inherited conditions where the production of platelets—blood cells that circulate and bind when they sense blood vessel damage—are dysregulated. Patients with ...

Their new model may pave the way for personalized treatment for platelet disorders. “Combining patient-derived cells and iPSCs with the 3D bone marrow model technology allows having a ...

Inherited platelet disorders are recognized as an important cause of mild to severe bleeding in both children and adults. Treatment of platelet disorders is mainly supportive.

Biomedical engineer and synthetic blood pioneer Anirban Sen Gupta and an international team of scientists report a new application for their synthetic platelets: treating the genetic condition ...

Biomedical engineers report a new application for their synthetic platelets: treating the genetic condition that prevents blood from clotting, Von Willebrand disease (VWD). The most common of all ...