The crystal structure the scientists developed can enable computational-based drug discovery to be used to target the i-motifs from the insulin gene, because when scientists know the specific 3D ...

Insulin played a prominent role in several scientific discoveries. For example, insulin was the first protein to be sequenced, a process by which scientists examine its amino acid structure.

Plasma-free amino acid (PFAA) profiles have been associated with a future risk of developing diabetes or cardiovascular disease in nondiabetic subjects. These PFAA alterations might predominantly ...

Insulin receptor tyrosine kinase substrate of 53-kDa protein (IRSp53) is now known to be a key factor in cytoskeleton reorganization. The human IRSp53 was identified as a binding partner with ...

Insulin and related peptides are key hormonal integrators of growth and metabolism in vertebrates. Recently, the amino acid and DNA sequences of insulin-related peptides in invertebrates have become ...

Insulin is one of the most commonly used therapeutic agents used in diabetes. While the structure of this complex protein has been studied in detail there were parts of the receptor for insulin ...

Archive Plasma Amino Acid Levels and Insulin Secretion in Obesity Authors: Philip Felig, M.D., Errol Marliss, M.D., and George F. Cahill, Jr., M.D. Author Info & Affiliations Published October 9, 1969 ...