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Peng Sang, Min Zhang, Yan Shi, Chunpu Li, Sami Abdulkadir, Qi Li, Haitao Ji, Jianfeng Cai, Inhibition of β-catenin/B cell lymphoma 9 protein−protein interaction using α-helix–mimicking ...
EpiTACs are an example of an extracellular protein degradation therapeutic. These are tissue-specific bispecific antibodies in which one arm binds a target and the other arm binds a degrader receptor.
Grove Biopharma is a private biotechnology company pioneering its proprietary Bionic Biologics ™ platform to develop novel therapies targeting intracellular protein-protein interaction.
RT-QuIC assays use fluorescence intensity detection of thioflavin T and cycled shaking to produce prion protein multimers when a PrP Sc prion seed is present (See AN 232). Figure 1.
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News Medical on MSNNew redox-sensitive pathway reveals how cells activate AMPK in response to metabolic stress
AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.
Hepatitis C virus (HCV) infections are a global health problem, with an estimated 70 million chronic infections worldwide, which can lead to hepatocellular carcinoma and cirrhosis of the liver. To ...
Annals of Botany, Vol. 124, No. 7 (December 2019), pp. 1185-1197, 1243 (14 pages) • Background and AimsThe nuclear factor Y (NF-Y) transcription factor complex is important in plant growth, ...
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