The researchers went on to demonstrate that, by deleting the super-enhancer or the hnRNPF gene in the cell lines, they could slow the growth of pancreatic cancer cells by more than 80 percent.

The researchers went on to demonstrate that deleting the super-enhancer or knocking out the hnRNPF gene in cell lines effectively slowed the growth of pancreatic cancer cells by more than 80%.

More information: Inderpreet Sur et al, Shared requirement for MYC upstream super-enhancer region in tissue regeneration and cancer, Life Science Alliance (2025). DOI: 10.26508/lsa.202403090 ...