In the US, the rate of ischemic stroke among adults aged 20 to 44 surged from 17 per 100,000 adults in 1993 to 28 per 100,000 in 2015. The risk of stroke death among young adults is also on the rise.

At least 17 factors contribute to dementia, stroke and late-life depression, according to an extensive review published Wednesday in the Journal of Neurology, Neurosurgery, and Psychiatry.