Bioengineering Dermo-Epidermal Skin Grafts with Blood and Lymphatic Capillaries. Science Translational Medicine, 2014; 6 (221): 221ra14 DOI: 10.1126/scitranslmed.3006894 ...

By Amanda W. Lund, PhD The prevailing model of lymphatic vessel involvement in cancer is that tumor cells use lymphatic vessels as passive escape routes. The more lymphatic vessels, the more ...

However, this route is slow. While cells in blood vessels and in most other lymphatic vessels are carried along by a flow of fluid, virtually no flow is present in lymphatic capillaries.

Together with the blood capillaries that were also engineered, this guarantees rapid, efficient vesicular supply of the skin graft. Up to now, this had been a major unsolved problem in molecular ...

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the ...

The results showed that lymphatic capillaries, which form an intimate connection with the stem cells in the crypt, produce a number of proteins known to be important for stem cell functioning.

Around 90% of the plasma that reaches tissues from the arterial blood capillaries returns through the venous capillaries and veins. The remaining 10% travels through the lymphatic system.

The cells that make up the walls of the finest of all lymphatic vessels have a lobate, oak leaf-like shape that makes them particularly resilient to changes in fluid volume. A similar cell shape ...

Institute for Basic Science. "Newly identified gut cells nurture lymph capillaries." ScienceDaily. ScienceDaily, 14 August 2020. <www.sciencedaily.com / releases / 2020 / 08 / 200814101701.htm>.

This indicates that the lymphatic capillaries need this overlap for the vessel to be able to expand without rupturing when the fluid pressure rises," says Mäkinen.