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Understanding how major histocompatibility complex class (MHC) molecules and peptides interact within the immune system is crucial for the advancement of biological sciences and medicine. A better ...
Jiansheng Jiang, Kannan Natarajan, Lisa F. Boyd, Giora I. Morozov, Michael G. Mage, David H. Margulies, Crystal structure of a TAPBPR–MHC I complex reveals the mechanism of peptide editing in antigen ...
David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...
In a breakthrough study published in Science, researchers unveiled an AI-driven platform capable of designing precision ...
New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased ...
Immunopeptidomics is a cutting-edge field focused on identifying and characterizing peptides presented by major histocompatibility complex (MHC) Class I and II molecules on cell surfaces. These ...
The importance of determining protein-peptide interactions extends to many areas of cellular signaling. To determine if the trained model could provide insights into the protein-peptide affinities for ...
Focusing on a group of proteins called Major Histocompatibility Complex-1 (MHC-1), the AI-based tool, in seconds, can classify the specific group of proteins unique for an individual and predict ...