We found that both resident fibroblasts and CAFs came from the splanchnic mesenchyme, a layer of cells in an embryo during early development." Lu Han, Ph.D., lead author of the publication ...

In August 2020, a clear embryo with neither the CDH1 mutation nor the BRCA-1 gene was implanted, but Melissa miscarried. None of the remaining embryos were mutation free, according to the lawsuit.

The researchers used an experimental model with an iPSC line carrying a lung mesenchyme-specific fluorescent reporter, meaning that cells that become lung mesenchymal were marked by green ...