As you age, maintaining a daily habit of walking can prevent cognitive decline, especially for those most at risk, a new ...

New University of Virginia School of Medicine research suggests an unexpected way doctors may be able to improve blood flow ...

Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

UCSF researchers have identified ADGRG1, a microglial receptor that helps clear amyloid beta plaques in Alzheimer’s disease.

Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic ...

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

Microglia, a type of brain immune cell, can gobble up amyloid beta protein, which clumps together into toxic aggregates ...

In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. Subscribe to our ...

Scientists at UCSF have identified a brain receptor, ADGRG1, that helps immune cells clear toxic plaques linked to ...

UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer's, ...

Impact of CD2AP deficiency in microglia in Alzheimer’s disease (AD). Microglial CD2AP levels are increased in AD, leading to elevated CSF1R signaling and C1q expression and cytoskeleton ...

A new study, published today in Nature Communications, offers clues into how APOE isoforms differentially affect human microglia function in Alzheimer's disease. The study, led by Dr Sarah Marzi ...