Chronic obstructive pulmonary disease (COPD) is a complex disease in which neutrophils play a central role. However, there are many different interactions with endothelial and pulmonary cells as ...

One of the key features of COPD is systemic inflammation. A blood test that checks for certain markers of inflammation may be helpful. The neutrophil-to-lymphocyte ratio (NLR) and eosinophil-to ...

The experimental group had significantly higher levels of white blood cells, neutrophils, C-reactive protein (CRP), serum amyloid A (SAA), neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein ...

which are involved in the migration of inflammatory neutrophils in COPD, and inhibitors of phosphodiesterase 4 (PDE4), a significant anti-inflammatory target. Table 1 Selected novel COPD pipeline ...

The new findings are the first to describe distributions and perturbations of low-density granulocyte and normal-density ...

Neutrophils in white blood cells may give clues to level of COPD risk. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing ...

Beyond our mechanistic studies in protease and neutrophil biology, we are characterizing the pattern of a variety of biomarkers in the progression of lung diseases such as COVID-19, CF, COPD, and IPF.

Meanwhile, COPD and control participants had similar ... an observational study assessing the role of neutrophil proteinase activity and the suitability of validated screening tools, Orphanet ...

First of all, it has become clear that the regulation of neutrophils in COPD follows different routes than the regulation of healthy neutrophils. Identifying the pathways that are altered and the ...