Journal of Industrial and Engineering Chemistry (2021). [2] A continuous-flow synthesis of primary amides from hydrolysis of nitriles using hydrogen peroxide as oxidant. Tetrahedron (2018).

Their method uses nitrile hydratase enzymes to transform aryl and alkyl nitriles into a primary amide intermediate. A catalyst, made from inexpensive, abundant copper, then tacks an aryl group ...

Depending on the conditions used, the reaction can also transform aldehydes into either primary amides or nitriles (Science 2019, DOI: 10.1126/science.aay9501).

The product selectivity in alcohol ammoxidation could be effectively controlled by tuning manganese oxide crystals, where nitriles are dominant products over α-Mn2O3-based catalysts, and MnO2 ...