For clinicians new to using autofluorescence for oral screening, this research offers an analytic technique to help discriminate between oral cancer/precancerous lesions and normal oral mucosa.

The autofluorescence properties of oral tissues vary based on anatomic site and pathologic diagnosis. [52–54] In normal squamous oral mucosa, autofluorescence in the UV and visible region of the ...

In cytologic scrapings from 275 heavy smokers with clinically normal mucosa, we found tetraploidy in four and aneuploidy in 19 persons (23 of 275; 8%). Twenty one (91%) of 23 persons with aneuploidy ...