Stem cell study reveals how infantile cystinosis causes kidney failure – and how to cure it This image, produced by a fluorescence microscope, shows a normal renal proximal tubule, the specific ...

New Role Of Inflammatory Protein In Polycycstic Kidney Disease Identified, Could Lead To Treatment Date: June 20, 2008 Source: Stowers Institute for Medical Research Summary: Scientists have ...

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the ...

Normal variations in glomerular filtration induce proportional changes in proximal tubule Na+ reabsorption. This "glomerulotubular balance" derives from flow dependence of Na+ uptake across luminal ...

Data show 60% of iscalimab-treated transplant patients have normal kidney histology at least 1 year after transplant vs 0% with tacrolimus (current standard of care) [1] Less than half of donated ...

This image, produced by a fluorescence microscope, shows a normal renal proximal tubule, the specific nephron segment in the kidney that is impaired in the rare disease infantile cystinosis. The ...

That finding means that the CRISPR genome-editing technique could be used to repair the defective genome and potentially cure the disease. “The normal gene can be introduced in the genome of ...