The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of ...

During interphase, individual chromosomes are not visible, and the chromatin appears diffuse ... begins with the abrupt fragmentation of the nuclear envelope into many small vesicles that will ...

We specialize in high throughput top down liquid chromatography-mass spectrometry. This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...