Share on Pinterest Researchers say circuits in the brain could help provide pain relief without the use of opioids. Westend61/Getty Images Researchers have identified an alternative pain control ...

These changes are important to understand, given that around 2.5 million adults in the U.S. have opioid use disorder, researchers said.There were more than 81,000 overdose deaths involving opioids ...

Alternative pain control circuits in the brain produce relief similar to opioids without the downsides Targeting a receptor for the neurotransmitter acetylcholine produces powerful analgesic ...

The U.S. Food and Drug Administration (FDA) has approved a new drug for the treatment of moderate-to-severe pain that is a non-opioid and carries less risks of addiction than opioids. Journavx ...

The study, published in Neuron in September, also showed that pain relief through this route did not induce tolerance, did not create withdrawals symptoms after treatment was stopped, and did not ...

Early animal tests suggest it can block pain at its root — all without the usual risks. But the real game-changer lies in how it works. While opioids flood the brain and body, affecting multiple ...

Pharmaceutical opioids, such as morphine and oxycodone, and illicit opioid drugs like heroin, affect the brain and body by binding to opioid receptors on the surface of cells in the nervous system.

Thirty years into the opioid crisis, we still struggle to find other options for pain relief. This hour, TED speakers explain new understandings of how the brain interprets pain and new ideas to cope.

Chronic pain, opioids and the body's own 'benzos' University of Leeds. Journal Journal of Clinical Investigation Funder Wellcome Trust, Medical Research Council, Biotechnology and Biological ...

Discover SBI-810, a promising non-addictive painkiller that avoids common opioid side effects and addiction risks, offering hope for chronic pain sufferers.

Opioids activate receptors in the brain to block pain signals and cause the release of endorphins—the body’s feel-good, natural painkillers—which is why we risk becoming addicted.