BOSTON -- For the first time, researchers have shown how Mullerian inhibiting substance (MIS), also known as anti-Mullerian hormone, a key reproductive hormone, suppresses follicle development and ...

Women with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive hormones, which may underlie reduced fertility ...

Aritro Sen, Hen Prizant, Allison Light, Anindita Biswas, Emily Hayes, Ho-Joon Lee, David Barad, Norbert Gleicher, Stephen R. Hammes, Androgens regulate ovarian follicular development by increasing ...

ATLANTA — Women with obesity have fewer ovarian follicles that remained static for longer and regressed more slowly compared with those found in women with normal weight, according to findings ...

This important study reports that two distinct waves of ovarian follicles contribute to oocyte production in mice. The paper provides large amounts of data that will benefit future studies, although ...

Generation of ovarian follicles from mouse pluripotent stem cells. Science, 2021; 373 (6552): eabe0237 DOI: 10.1126/science.abe0237 ...

Ovarian development requires the combination of germ cells and several types of somatic cells. Among these, granulosa cells play a key role in follicle formation and support for oogenesis.

Women with obesity, even those with regular menstrual cycles, have suppressed ovarian follicle development and reduced production of reproductive hormones, which may underlie reduced fertility ...