Werner syndrome is a rare genetic condition that causes people to age faster than normal, leading to early gray hair, cataracts, and other age-related health problems.

Werner syndrome is a rare genetic condition that causes people to age faster than normal, leading to early gray hair, cataracts, and other age-related health problems.

Werner syndrome leads to signs of aging much earlier than normal, including problems such as cataracts, hair loss, and atherosclerosis by age 20 to 30. The team found that when the WRN gene is ...

Affecting approximately 1 in 380,000 to 1 in 1,000,000 people globally (GeneReviews), Werner syndrome is caused by mutations that impair DNA repair, leading to cellular aging decades ahead of ...

Werner syndrome is a rare genetic disorder that causes accelerated aging due to mutations in the WRN gene, which disrupts normal cell functions. The WRN gene is typically responsible for essential ...

To model this disease, the Company's study utilized the Sen57wrn-/-ND6-/+ zebrafish model, which replicates key features of Werner Syndrome, including telomere loss, mitochondrial dysfunction ...

A new research paper was published in Aging (Aging-US) on April 2, 2025, as the cover of Volume 17, Issue 4, titled "Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional ...

Telomir-1 tripled telomere length and reversed weight and muscle loss in a preclinical model of Werner Syndrome. ROS levels dropped by up to 50%, and no deaths were reported in treated groups over ...

METHODOLOGY: Researchers analyzed data from 51 patients with WS enrolled in the Japanese Werner Syndrome Registry between 2016 and 2022. The mean age of participants was 48.8 years; 52.9% were men.