Strikingly, enhancer regions can be thousands of DNA base pairs away from the genes they control. The 3D looping of DNA brings enhancers and the promoters of their target genes into contact.

Long distance haul: Regulatory proteins (gold balls) bind to enhancer regions (light blue) and promoter regions (pink) of DNA to form clusters that enable transcription (purple). Summary Through ...

The promoter is usually located right next to the gene, and is where the protein that carries out transcription attaches to the DNA. Enhancers, on the other hand, are often many hundreds of ...

The promoter is usually located right next to the gene, and is where the protein that carries out transcription attaches to the DNA. Enhancers, on the other hand, are often many hundreds of ...

The promoter is usually located right next to the gene, and is where the protein that carries out transcription attaches to the DNA. Enhancers, on the other hand, are often many hundreds of ...

After a segment of non-protein–coding DNA called an enhancer gets close to its target gene, it tends to stick around, staying attached to the gene’s promoter while the gene’s transcription ...

As an example, the researchers focused on a gene called Nanog, a 770,000-base length of DNA on chromosome 6, which has a promoter and three enhancer regions and is known to undergo transcriptional ...

However, limiting the genomic regions to be analyzed, effects of DNA methylation on other regions (e.g., enhancer 6) and functions remain unexplored. 2 The Study and the Accomplishment ...

Strikingly, enhancer regions can be thousands of DNA base pairs away from the genes they control. The 3D looping of DNA brings enhancers and the promoters of their target genes into contact.

Long distance haul: Regulatory proteins (gold balls) bind to enhancer regions (light blue) and promoter regions (pink) of DNA to form clusters that enable transcription (purple). Summary Through ...