By providing a tangible example of centralized monitoring implementation, the paper showcases the benefits of utilizing a risk-based approach to clinical trial monitoring, significantly reducing ...

As clinical trial complexities grow, ICH E6 (R3) updates emphasize smarter monitoring, greater participant focus, and a stronger tech role.

The American Gastroenterology Association (AGA) Institute issued new clinical practice guidelines, providing evidence-based recommendations for managing hepatitis B reactivation (HBVr) in at-risk ...

Decentralized Clinical Trials (DCTs) are transforming how we collect clinical data, but this evolution brings unprecedented challenges in data quality, complexity, and integration.

More information: Patient-Reported Outcomes for Low-Risk Ductal Carcinoma In Situ A Secondary Analysis of the COMET Randomized Clinical Trial, JAMA Oncology (2024). DOI: 10.1001/jamaoncol.2024.6556 ...

While IL-17 blocking agents are linked to an increased risk for candidiasis, bimekizumab, which blocks two proteins ...

Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast ...

More recently, the phase 3 QuiRedex trial evaluated early treatment with lenalidomide plus dexamethasone (Rd) as compared with active monitoring in patients with high-risk smoldering multiple ...

Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast ...

News GlobeNewswire Radiopharm Theranostics Accelerates 177Lu-RAD204 Phase 1 Dose Escalation Clinical Trial Based on Positive Recommendation from Data Safety and Monitoring Committee (DSMC) ...