The basis of SPR analysis is the measurement of changes in the resonance angle as molecules bind to or dissociate from the metal surface. This change can be detected and quantified, providing detailed ...

The new BI-4500 SPR system provides multiple channel flow modes and delivers high quality binding response for low immobilization and small molecule (<100 Da) detection. Equipped with BI ...

Surface plasmon resonance (SPR) spectroscopy is a technique to detect biomolecular binding interactions. In SPR, one molecular partner is immobilized on a metallic film. Light excites surface ...

This binding facilitates RNA polymerase activity and transcription of nearby genes. At the same time, however, other amino acids would bind to negative regulatory proteins called repressors ...

Early identification of nonspecific binding to control proteins is crucial in many SPR applications. In small molecule characterization and screening, binding to serum proteins, such as BSA and HSA, ...

The Biacore T200 uses surface plasmon resonance (SPR) technology to precisely monitor label-free binding activity between proteins, peptides, nucleic acids, carbohydrates, lipids or small drugs ...