Classical MHC-I molecules are comprised of three major parts: a peptide antigen consisting of 8 to 15 amino acids; a light chain that is the same for all MHC-I molecules; and a highly polymorphic ...

MHC-peptide exchange is considered to be tricky by researchers. However, with the right set of tools and protocols, this peptide-MHC exchange can be done easily, quickly, and provides robust ...

Our core provides customized MHC/peptide tetramers for identification of antigen-specific T lymphocytes by flow cytometry. Tetramers and/or their derivatives are provided for research purposes only.

MHC-I is a heterodimer of beta-2-microglobulin (β 2 m) and a glycosylated heavy chain. The MHC-I molecules are loaded with peptides in the endoplasmic reticulum (ER), including viral peptides.

In a breakthrough for the treatment of aggressive solid cancers, researchers have developed a novel cancer therapy that targets proteins inside cancer cells that are essential for tumor growth and ...