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They included 578 children with steroid-sensitive nephrotic syndrome diagnosed from 1996 to 2019. Median age at diagnosis was 3.7 years, and 64% were boys. Of these patients, ...
Steroid-resistant nephrotic syndrome (SRNS) is a disease characterized by hypoalbuminemia, proteinuria, edema and hyperlipidemia, and a cause of chronic kidney disease in the pediatric population.
The children were aged 3 to 16 years, with steroid-dependent nephrotic syndrome. All children were naïve to steroid-sparing agents prior to enrollment, and all had undergone kidney biopsy to ...
The multicenter open-label trial included 172 patients ages 1 to 4 years with newly diagnosed steroid-sensitive nephrotic syndrome. All achieved complete remission by week 6 of therapy with daily ...
Mycophenolate mofetil may be a viable alternative to steroids for induction therapy in children with steroid-sensitive idiopathic nephrotic syndrome, researchers found in a study. Investigators ...
Tacrolimus prolongs relapse-free survival in pediatric patients with steroid-dependent or frequently relapsing nephrotic syndrome. Tacrolimus significantly extends relapse-free survival compared ...
In a study of adult patients with minimal change nephrotic syndrome, tacrolimus plus low-dose steroids achieved a complete remission rate similar to high-dose steroid therapy alone. Tacrolimus may ...
However, doctors recommend that people taking steroid medications for nephrotic syndrome should also take vitamin D or calcium supplements. This is because steroid medications can affect a person ...
They included 578 children with steroid-sensitive nephrotic syndrome diagnosed from 1996 to 2019. Median age at diagnosis was 3.7 years, and 64% were boys. Of these patients, ...
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