All patients had steroid-dependent, idiopathic nephrotic syndrome. The new therapies were introduced once the children were in remission; steroid treatment was then withdrawn over a 2-month period.

Although initially, many children with idiopathic nephrotic syndrome respond to steroid therapy, a repeated course for patients with relapses often causes significant steroid toxicity. Patients ...

Tacrolimus prolongs relapse-free survival in pediatric patients with steroid-dependent or frequently relapsing nephrotic syndrome. Tacrolimus significantly extends relapse-free survival compared ...

The children were aged 3 to 16 years, with steroid-dependent nephrotic syndrome. All children were naïve to steroid-sparing agents prior to enrollment, and all had undergone kidney biopsy to ...

Corticosteroids, also called steroids, are a common treatment for nephrotic syndrome in children. Often these anti-inflammatory medicines relieve symptoms enough to put the disease into remission ...

They included 578 children with steroid-sensitive nephrotic syndrome diagnosed from 1996 to 2019. Median age at diagnosis was 3.7 years, and 64% were boys. Of these patients, ...

The immunosuppressant drug tacrolimus may significantly improve relapse-free survival vs. mycophenolate mofetil for children with frequently relapsing nephrotic syndrome, according to study data.

The presence of anti-rituximab antibodies does not change the response that pediatric patients with steroid-dependent nephrotic syndrome have to rituximab treatment, according to a speaker from ...

Mutations in the NUP160 gene, which encodes one protein component of the nuclear pore complex nucleoporin 160 kD, are implicated in steroid-resistant nephrotic syndrome, an international team ...

The subjects were 10 patients with nephrotic syndrome of diverse causes, each of whom had failed to respond to 60 mg. or more of prednisone daily, administered for three weeks to four months.

They included 578 children with steroid-sensitive nephrotic syndrome diagnosed from 1996 to 2019. Median age at diagnosis was 3.7 years, and 64% were boys. Of these patients, ...