They discovered that drugs known as carbonic anhydrase inhibitors – of which the ... characterised by the build-up in the brain of tau protein ‘aggregates’ within nerve cells.

Tau is a protein that is found in cells of the central ... Furthest ahead is TauRx, which has a tau aggregation inhibitor called LMTX in a phase 2/3 trial (LUCIDITY) with results due in 2021 ...

Scientists have only shifted focus more recently to developing anti-tau therapies. Of the tau aggregation inhibitors and antibodies that they have generated so far, many of them do not efficiently ...

In the current study, the team dug deeper into how TYK2 transforms tau into a protein that aggregates ... our findings suggest that partial inhibition of TYK2 could thus be a strategy to reduce ...

The new research also found that tau protein in the brain, considered a hallmark of Alzheimer’s disease, may initially play a protective role against viral infections. “Identifying health ...

Researchers identified a key protein as a potential therapeutic target for stopping the body's immune system from mistakenly attacking itself, offering new hope for treating autoimmune diseases and ...