THZ (diuretics) No No, in relation to MI or stroke event ns E 701 [14] GNB3 ADD1 PTP- THZ Yes No, in relation to BP or CHD event ns E 12,362 [8] A mixed (34.4% A) ADD1 Naive and PTP+ 4 weeks HCTZ ...

Mendelian Randomization Analysis of Genetic Proxies of Thiazide Diuretics and the Reduction of Kidney Stone Risk. JAMA Network Open, 2023; 6 (11): e2343290 DOI: 10.1001/jamanetworkopen.2023.43290 ...

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for ...

Given that thiazide diuretics bind to NCC from outside the cell 2, we hypothesized that wild-type NCC might not be suitable for determining the polythiazide-bound structure.

The SGLT2 inhibitor didn't relieve congestion more effectively than a 'thiazide-like' diuretic when added to furosemide in loop-diuretic–resistant patients with acute heart failure.

Hsi, R. S., et al. (2024) Thiazide Dose, Urine Calcium, and Symptomatic Kidney Stone Events. JAMA Network Open. doi.org/10.1001/jamanetworkopen.2024.28953 Be the first to rate this article ...