Thus, in order totreat cutaneous malignancies such as melanoma-or squamous-cell carcinoma with recombinant Apo2L/TRAIL (ref. 7), it is critically important not to trigger premature apoptosis of ...

Combining an existing small-molecule protein therapy called tumor necrosis factor related apoptosis-inducing ligand (TRAIL) with focused ultrasound (FUS) can significantly reduce tumor size and ...

Histone-deacetylase inhibitors (HDACIs) have successfully entered clinical trials, but the basis of their antitumour activity is not clear. Two papers published in the January issue of Nature ...

More information: Abigail R. Fabiano et al, Applying Ultrasound to Mechanically and Noninvasively Sensitize Prostate Tumors to TRAIL‐Mediated Apoptosis, Advanced Science (2025). DOI: 10.1002 ...