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In β-thalassemia, decreased β-globin synthesis leads to red blood cell loss, iron overload and anemia. Using a mouse model of this disease, Huihui Li et al. now describe a new approach for ...
Original Article Archive Effect of Transferrin Saturation on Iron Absorption in Man Authors: Major Munsey S. Wheby and Genoveva Umpierre, B.S. Author Info & Affiliations Published December 31, 1964 ...
Unsaturated iron-binding capacity (UIBC). This measures how much transferrin is not yet bound to iron. Total iron-binding capacity (TIBC). This is the total amount of iron in your blood plus the UIBC.
The consequent anemia, combined with loss of the ferri-transferrin signal, results in low hepcidin levels, despite iron overload. 68,69 In patients with aceruloplasminemia 70 (OMIM number, 604290 ...
Transferrin saturation was also associated with reductions in all aging metrics. PhenoAgeAccel and GrimAgeAccel were associated with serum iron and transferrin levels, the latter of which showed ...
Individuals with a transferrin saturation of more than 45% but a normal dietary iron intake were not at increased risk (hazard ratio [HR], 1.02; 95% CI, 0.69 - 1.49).
The University of Kent's School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, have identified that a glycoprotein known as transferrin may ...
University of Kent. "Transferrin identified as potential contributor to COVID-19 severity." ScienceDaily. ScienceDaily, 3 August 2020. <www.sciencedaily.com / releases / 2020 / 08 / 200803120139.htm>.
This study was supported by the National Institutes of Health and the Washington Research Foundation. UW/Fred Hutch Cancer Consortium members Roland Strong and Jim Olson contributed to this work.
We have studied the role of human transferrin and of exogenous iron on early growth and development of schistosomula of Schistosoma mansoni in vitro, as determined by developmental achievement and ...
as the respective estimates of total iron and transferrin-bound iron concentrations. For those with a more numerical bent, Matlab code for this maximization procedure is given in the Appendix, which ...