Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic ...

Problems with this 3D structure are associated with many diseases including developmental disorders and cancer. Almost 12% of genomic regions in breast cancer cells have incurred issues with their ...

Almost 12% of genomic regions in breast cancer cells have incurred issues with their chromatin structure, while other structural issues are known to cause T-cell acute lymphoblastic leukemia.

Abstract The three-dimensional (3D) chromatin structure of Epstein–Barr virus (EBV) within host cells and the underlying mechanisms of chromatin interaction and gene regulation, particularly those ...

Defense Secretary Pete Hegseth has ordered a reduction of general and flag officers and directed the Army to make force structure changes, including consolidating commands.

Our genome is organized into chromatin, a dynamic and modular structure made of nucleosomes. Chromatin organization controls access to the DNA sequence, playing a fundamental role in cell identity and ...

Scientists complete largest wiring diagram and functional map of the brain to date The MICrONS Project is considered the most complicated neuroscience experiment ever attempted Date: April 9, 2025 ...

We provide an integrated analysis of chromatin accessibility and transcriptional profiles in paired human SAT and OVAT samples, offering new insights into the regulatory landscape of adipose tissue ...

The structure of chromatin at the nucleosome level inside cells is still incompletely understood. Here we present in situ electron cryotomography analyses of chromatin in both G1 and metaphase RPE-1 ...

In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, will describe how chromatin mapping assays such as CUT&RUN, ATAC-seq, and ...

As for chromatin 3D structure, BMI1s have been reported to maintain the compartment domains (CDs) generally, but the mechanism by which they function remains elusive.