While it can be helpful for learners to begin with the linear presentation of how stretches of DNA form genes, this oversimplification undersells the significance of the genome's 3D structure.

In a paper published on aBIOTECH, the authors revealed the joint regulation of chromatin structure and gene expression by BMI1s, the core components of Arabidopsis PRC1, and the condensin complexes.

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

Almost 12% of genomic regions in breast cancer cells have incurred issues with their chromatin structure, while other structural issues are known to cause T-cell acute lymphoblastic leukemia.