Inside the nucleus of a cell, the chromatin fiber interacts with itself to condense into a chromosome. The chromatin fiber also supports gene expression and replication of chromosomal DNA.

A new imaging technique (ChromEMT) enables the visualization of the local polymer structure and global 3D organization of chromatin in the nucleus of intact interphase and mitotic human cells.

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Imaging Chromatin to Deduce Function from Form. Researchers describe their tools for probing how the physical shape of the genome affects genes’ function. ... 1860, provide one of the first ...

Using computer simulations, MIT chemists have now discovered how these bodies interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets within ...

The nucleus is also home to small bodies called nucleoli ... One of the key functions of the nucleoli is to produce ribosomal RNA, ... However, once chromatin was introduced into the model, ...

A team of scientists has uncovered the physical principles - a series of forces and hydrodynamic flows - that help ensure the proper functioning of life's blueprint.

Inside a nucleus, chromosomes jumble together like a game of Twister. This can bring regulatory elements, such as enhancers, from one chromosome into contact with genes from another chromosome, ...

Their research, published on the cover of Nature Biomedical Engineering on Dec. 2 and titled "Nuclear Deformation Guides Chromatin Reorganization in Cardiac Development and Disease," found that ...

Some regions of this so-called chromatin contain genes, that is information about proteins, and are known as euchromatin. They are typically found in the interior of the nucleus.