A joint study has developed new 3D models that accurately show chromosomes’ shape, which is more complex than the popular X-shaped blob, and how the DNA within them folds up.

A new method for visualising chromosomes is painting a truer picture of their shape, which is rarely like the X-shaped blob of DNA most of us are familiar with. Scientists at the BBSRC-funded Babraham ...

Structural maintenance of chromosomes (SMC) complexes — cohesin, condensin and the SMC5/6 complex — regulate sister chromatid cohesion, chromosome condensation, and DNA replication, repair and ...

These motors play distinct roles in manipulating chromosome structure. Swimming motors, similar to RNA polymerases—enzymes that copy DNA sequences into RNA—help expand and contract the ...

To understand chromosome reshuffling, look to the genome's 3-D structure. ScienceDaily . Retrieved May 14, 2025 from www.sciencedaily.com / releases / 2012 / 02 / 120216134336.htm ...

This indicates that the basic chromosome structure had been preserved over 50,000 years in ice, even as the underlying chromosome had decayed into ever-smaller fragments.

A few years ago, people were focusing on the lack of human genetic diversity. At the level of individual DNA bases, any two humans were well over 99 percent identical. With the completion of the ...

"This research provides a deeper understanding of how motorized processes shape chromosome structures and influence cellular functions," said Peter Wolynes, study co-author and the D.R. Bullard ...

Ultrastructure of a condensed chromosome-like structure in a cyanobacterium. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2016 / 10 / 161020100557.htm.

Research led by Osaka University showed that a regulatory protein of chromosome structure (cohesin) is essential for proper maintenance of gene expression in the developing brain. Reduced cohesin ...