Now, researchers present a high-resolution structure of the monkeypox virus DNA polymerase holoenzyme—a complex that plays a key role in the genome replication process of the virus.

Until now, the structure and function of the Nipah virus polymerase remained poorly understood. Unraveling this piece of the viral apparatus is the critical first step toward developing ways to ...

In the new study, researchers homed in on a part of the viral machinery called the viral polymerase complex, a group of proteins the virus uses to copy its genetic material, spread, and infect cells.

A recent study in Nature Communications examined how RNA polymerase I (Pol I) responds to abasic (Ap) site formation—the most common type of DNA damage. The researchers found that Pol I helps ...