Once dismissed as “junk,” pieces of ancient viral DNA in our genome are now known to help control which genes are turned on or off.

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

San Diego BioMed congratulates the Gilbert Lab for their recent publication! Read @ The EMBO Journal: Professor Gilbert has provided an engaging commentary on this manuscript and his lab’s work below ...

Here, we reconstitute replication of physiologically derived structure‐forming sequences to find that a single G4 or iM arrest DNA replication. Direct single‐molecule structure detection within ...

DNA replication is an essential process that requires very careful regulation. Tsutomu Katayama and colleagues describe the many ways in which the initiation of chromosomal DNA replication is ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.