During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

San Diego BioMed congratulates the Gilbert Lab for their recent publication! Read @ The EMBO Journal: Professor Gilbert has provided an engaging commentary on this manuscript and his lab’s work below ...

Here, we reconstitute replication of physiologically derived structure‐forming sequences to find that a single G4 or iM arrest DNA replication. Direct single‐molecule structure detection within ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

Recent findings reveal that early mouse embryos replicate their DNA in a unique, uniform manner, which changes after the embryo grows beyond four cells. This early-stage replication is slower and more ...

2 Structure of replication origin regions DNA replication initiation in bacteria starts with replication initiation proteins binding with the specific motifs within a well-defined origin region ...