Scientists have reached a new milestone in decoding the human genome, unlocking complex regions once believed to be too difficult to study. Researchers used long-read sequencing to analyze the DNA of ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

A new study shows that over 99% of the human genome can be accurately assembled by focusing on 65 diverse humans.

In ExIGS, expansion microscopy is integrated with in situ genome sequencing to simultaneously sequence genomic DNA and image nuclear proteins at nanoscale resolution within single cells.

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars ...

Thus, elevated sequencing errors at non-B DNA motifs should be considered in low-read-depth studies (single-cell, ancient DNA, and pooled-sample population sequencing) and when scoring rare variants.

In the late 2000s, IBM proposed the idea of DNA transistors, conceptualized with a dielectric metal sandwich structure and electrostatic traps to simultaneously allow ratchet-like control and sensing ...